Risperidone augmentation of SRI treatment for refractory obsessive-compulsive disorder.

@article{Saxena1996RisperidoneAO,
  title={Risperidone augmentation of SRI treatment for refractory obsessive-compulsive disorder.},
  author={Sanjaya Kumar Saxena and Desheng Wang and Alexander Bystritsky and Lewis Baxter},
  journal={The Journal of clinical psychiatry},
  year={1996},
  volume={57 7},
  pages={303-6}
}
BACKGROUND Although serotonin reuptake inhibitors (SRIs) are the mainstay of pharmacologic treatment for obsessive-compulsive disorder (OCD), many patients do not have an adequate response to these medications. One approach to treating SRI-refractory OCD patients has been to add other classes of medications to the SRI. We predicted that augmentation with risperidone would alleviate symptoms in SRI-refractory OCD patients. METHOD 21 patients were treated openly with the combination of an SRI… CONTINUE READING