Risperidone and ritanserin but not haloperidol block effect of dizocilpine on the active allothetic place avoidance task.

@article{BubenkovValeov2008RisperidoneAR,
  title={Risperidone and ritanserin but not haloperidol block effect of dizocilpine on the active allothetic place avoidance task.},
  author={Věra Buben{\'i}kov{\'a}-Vale{\vs}ov{\'a} and Ales Stuchlik and Jan Svoboda and Jan physician Bure{\vs} and Karel Vale{\vs}},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 3},
  pages={
          1061-6
        }
}
Spatial working memory or short-term place memory is impaired in schizophrenia. The efficiency of antipsychotic drugs, particularly of typical antipsychotics, on cognitive deficit in schizophrenia remains disputable. Inhibition of serotonin (5-HT) 2A/2C receptors is important for cognitive improvement in schizophrenic patients treated with antipsychotics. The aim of the present work was to establish the effect of the 5-HT2A/2C receptor antagonist ritanserin (2.5 or 5 mg/kg), the dopamine D2… CONTINUE READING

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