Risperidone and haloperidol augmentation of serotonin reuptake inhibitors in refractory obsessive-compulsive disorder: a crossover study.

@article{Li2005RisperidoneAH,
  title={Risperidone and haloperidol augmentation of serotonin reuptake inhibitors in refractory obsessive-compulsive disorder: a crossover study.},
  author={Xiaohua Li and R. Scipioni May and Lelland C Tolbert and Warren T. Jackson and James M Flournoy and Lewis Baxter},
  journal={The Journal of clinical psychiatry},
  year={2005},
  volume={66 6},
  pages={736-43}
}
BACKGROUND Although serotonin reuptake inhibitors (SRIs) are the first-line treatment for obsessive-compulsive disorder (OCD), approximately half of patients with OCD do not respond adequately to SRI monotherapy. Patients with predominant obsessions are common in OCD and are often difficult to treat, necessitating adjunctive treatment. METHOD This was a 9-week, double-blind, placebo-controlled, crossover study comparing the benefits of 2-week adjunctive treatments with risperidone… CONTINUE READING

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Treatment-refractory obsessive compulsive disorder.

Progress in neuro-psychopharmacology & biological psychiatry • 2016
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