Risperidone Improves Behavioral Symptoms in Children with Autism in a Randomized, Double-Blind, Placebo-Controlled Trial

@article{Pandina2007RisperidoneIB,
  title={Risperidone Improves Behavioral Symptoms in Children with Autism in a Randomized, Double-Blind, Placebo-Controlled Trial},
  author={Gahan Pandina and Cynthia A. Bossie and Eriene A Youssef and Young Hong Zhu and Fiona Dunbar},
  journal={Journal of Autism and Developmental Disorders},
  year={2007},
  volume={37},
  pages={367-373}
}
Subgroup analysis of children (5–12 years) with autism enrolled in an 8-week, double-blind, placebo-controlled trial of risperidone for pervasive developmental disorders. The primary efficacy measure was the Aberrant Behavior Checklist-Irritability (ABC-I) subscale. Data were available for 55 children given risperidone (n = 27) or placebo (n = 28); mean baseline ABC-I ( ± SD) was 20.6 (8.1) and 21.6 (10.2). Risperidone [mean dose ( ± SD): 1.37 mg/day (0.7)] resulted in significantly greater… CONTINUE READING
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