Risky business: Microhomology-mediated end joining.

@article{Sinha2016RiskyBM,
  title={Risky business: Microhomology-mediated end joining.},
  author={Supriya Sinha and Diana D. Villarreal and Eun Yong Shim and Sang Eun Lee},
  journal={Mutation research},
  year={2016},
  volume={788},
  pages={
          17-24
        }
}
Prevalence of microhomology (MH) at the breakpoint junctions in somatic and germ-line chromosomal rearrangements and in the programmed immune receptor rearrangements from cells deficient in classical end joining reveals an enigmatic process called MH-mediated end joining (MMEJ). MMEJ repairs DNA double strand breaks (DSBs) by annealing flanking MH and deleting genetic information at the repair junctions from yeast to humans. Being genetically distinct from canonical DNA DSB pathways, MMEJ is… CONTINUE READING

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