Risks on N-acetyltransferase 2 and bladder cancer: a meta-analysis.

@article{Zhu2015RisksON,
  title={Risks on N-acetyltransferase 2 and bladder cancer: a meta-analysis.},
  author={Zongheng Zhu and Jinshan Zhang and Wei Jiang and Xianjue Zhang and Youkong Li and XiaoMing Xu},
  journal={OncoTargets and therapy},
  year={2015},
  volume={8},
  pages={3715-20}
}
BACKGROUND It is known that bladder cancer disease is closely related to aromatic amine compounds, which could cause cancer by regulating of N-acetylation and N-acetyltransferase 1 and 2 (NAT1 and NAT2). The NAT2 slowed acetylation and would increase the risk of bladder cancer, with tobacco smoke being regarded as a risk factor for this increased risk. However, the relationship between NAT2 slow acetylation and bladder cancer is still debatable at present. This study aims to explore… CONTINUE READING

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