Risks of Thrombosis and Rehemorrhage During Early Management of Intracranial Hemorrhage in Patients With Mechanical Heart Valves.

Abstract

Intracranial hemorrhage in patients with mechanical heart valves carries a risk of thrombosis and of rehemorrhage. Because interruption of anticoagulation with a mechanical heart valve may lead to thrombotic events, cardiologist recommendations generally lean toward minimizing the time off anticoagulation, although valve guidelines do not specifically address the duration of anticoagulation interruption (1,2). At the same time, when anticoagulation is resumed in these patients, there is a risk of recurrent hemorrhage, and longer periods of anticoagulation interruption should, in theory, reduce the risk of rehemorrhage. Because this scenario is rare, the extent of these 2 competing risks is poorly understood. Data regarding these risks come from small single-center retrospective case

DOI: 10.1016/j.jacc.2015.07.063

Cite this paper

@article{Flint2015RisksOT, title={Risks of Thrombosis and Rehemorrhage During Early Management of Intracranial Hemorrhage in Patients With Mechanical Heart Valves.}, author={Alexander C Flint and Ramesh Lingamneni and Vivek A Rao and Sheila L Chan and Xiushui Ren and Jasmeen Pombra and J Claude Hemphill and Robert O Bonow}, journal={Journal of the American College of Cardiology}, year={2015}, volume={66 15}, pages={1738-9} }