• Corpus ID: 40264064

Risks associated with long-term benzodiazepine use.

  title={Risks associated with long-term benzodiazepine use.},
  author={Brian Johnson and Jon Streltzer},
  journal={American family physician},
  volume={88 4},
Many patients underestimate the degree of impairment caused by benzodiazepines. Benzodiazepines increase the risk of addiction, withdrawal, cognitive decline, motor vehicle crashes, and hip fracture. The risk of overdose is particularly great when combined with sedative drugs such as opioids or alcohol. 

Association of New Perioperative Benzodiazepine Use With Persistent Benzodiazepine Use

While a relatively small percentage of surgical patients in this cohort study were prescribed Benzodiazepines in the perioperative period, 1 in 5 of these patients went on to persistent benzodiazepine use.

Substance Related and Addictive Disorders

Substance abuse is a major problem in consultation liaison psychiatry, disproportionate to the degree of substance abuse in the community. Twenty to thirty percent of consultations in a general

Opioids, benzodiazepines, and COVID‐19: A recipe for risk

The authors found that among patients admitted with COVID‐19, almost 1 in 4 receives an opioid and more than 1 in 10 receive a benzodiazepine during hospitalization, suggesting that physicians may be appropriately wary of prescribing these medications in this population.

Association between antidepressants and falls in Parkinson’s disease

The use of antidepressants was independently associated with falls in a PD cohort after considering for confounding variables such as age and measures of disease progression, which should be considered before claiming the use of psychotropic drugs as causative.

Treating Insomnia in Older Adult Patients: Limiting Benzodiazepine Use

Insomnia in older adults should ideally be treated with a non-benzodiazepine receptor agonist; if indicated, they may be used, but should be closely monitored and tapered to avoid long-term adverse problems (direct or from withdrawal).

Is there a link between the use of benzodiazepines and related drugs and dementia? A systematic review of reviews

Although hampered by the heterogeneity between the studies, the present findings suggest an association between BZDs/BZRDs use and increased risk of dementia in older adults.

Drugs of Abuse and Addiction - Overview and Current Status

    Khanh Nd
    Psychology, Biology
    Journal of Neurology and Neurological Disorders
  • 2018
Citation: Khanh ND (2018) Drugs of Abuse and Addiction Overview and Addiction Status and Current Status.

Patterns in Outpatient Benzodiazepine Prescribing in the United States

The use of benzodiazepines in ambulatory care increased substantially from 3.8% to 7.4% of visits, including coprescribing with other sedating medications, and the use among psychiatrists was stable but increased among all other types of physicians.

The influence of prescriber and patient gender on the prescription of benzodiazepines: results from the Florida Medicaid Dataset

Male prescribers are more likely to prescribe Benzodiazepine (BZD) prescription, and male patients areMore likely to receive BZDs.

Drugs of abuse

The diagnosis and management of benzodiazepine dependence

    H. Ashton
    Medicine, Psychology
    Current opinion in psychiatry
  • 2005
Benzodiazepine dependence could be prevented by adherence to recommendations for short-term prescribing (2–4 weeks only when possible), and withdrawal from dependent patients is feasible and need not be traumatic if judiciously, and often individually, managed.

The effects of benzodiazepines on cognition.

Findings suggest that patients should be advised of potential cognitive effects when treated long term with benzodiazepines, although they should also be informed that the impact of such effects may be insignificant in the daily functioning of most patients.

Risk of Fractures Requiring Hospitalization After an Initial Prescription for Zolpidem, Alprazolam, Lorazepam, or Diazepam in Older Adults

To determine whether zolpidem is a safer alternative to benzodiazepines, a large number of patients have taken these drugs and the results suggest that they are safe to treat anxiety and insomnia.

The role of a prescription in anxiety medication use, abuse, and dependence.

Results indicate that prescription for anxiety medications is associated with nonmedical use of these medications, although the direction of causality cannot be determined in this study.

The pharmacologic treatment of anxiety disorders: a review of progress.

Findings suggest that both selective serotonin reptake inhibitors and serotonin-norepinephrine reuptake inhibitors are useful first-line agents for most of the anxiety disorders, particularly given the frequent comorbidity with mood disorders.

Psychotropic drug prescribing in the United States: extent, costs, and expenditures.

Currently available data on psychotropic drug prescribing in the United States is presented and the various psychotropic drugs are divided into their traditional categories based on pharmaco-logic properties and labeled indications: anxiolytic, hypnotic, antidepressant, and antipsychotic.

Management of common sleep disorders.

Obstructive sleep apnea, defined as difficulty initiating or maintaining sleep that results in daytime impairment, is diagnosed using history findings and treated with cognitive behavior therapy, with or without sleep hypnotics.