Risks and benefits of splenectomy versus no splenectomy for hereditary spherocytosis--a personal view.

@article{Schilling2009RisksAB,
  title={Risks and benefits of splenectomy versus no splenectomy for hereditary spherocytosis--a personal view.},
  author={Robert F. Schilling},
  journal={British journal of haematology},
  year={2009},
  volume={145 6},
  pages={728-32}
}
Splenectomy is indicated in hereditary spherocytosis to relieve symptoms due to anaemia or splenomegaly, reverse growth failure or skeletal changes due to over-robust erythropoiesis, and prevent recurrent gallstones. A life-long risk of bacterial infection has been recognised for many years as a concomitant cost of splenectomy. The scope of this risk has expanded to include a number of organisms beyond the triad of pneumococcus, meningococcus, and haemophilus influenzae. Recently, it has been… CONTINUE READING
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