Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex.

@article{Bottini2005RiskOT,
  title={Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex.},
  author={Nunzio Bottini and Gian Franco Meloni and Paola Lucarelli and Ada Amante and Patrizia Saccucci and Fulvio Gloria-Bottini and Egidio Bottini},
  journal={Diabetes/metabolism research and reviews},
  year={2005},
  volume={21 4},
  pages={353-8}
}
BACKGROUND We have investigated the possible role of ACP1 (also known as cLMWPTP: cytosolic low molecular weight phosphotyrosine phosphatase), a highly polymorphic enzyme involved in signal transduction of T-cell receptor, insulin receptor and other growth factors in the relationship between maternal age at delivery and risk of type 1 diabetes in the offspring. METHODS One hundred and eighty-nine consecutive children with type 1 diabetes (TIDM) diagnosed at the Department of Pediatrics of the… CONTINUE READING