Risk of therapy-related leukaemia and preleukaemia after Hodgkin's disease. Relation to age, cumulative dose of alkylating agents, and time from chemotherapy.

Abstract

391 patients treated intensively for Hodgkin's disease were followed for up to 15 years to evaluate the risk of therapy-related acute non-lymphocytic leukaemia (t-ANLL) and preleukaemia. Only two independent factors, patient age and cumulative dose of alkylating agents, were related to the risk of t-ANLL. The hazard rate of t-ANLL was roughly proportional… (More)

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Cite this paper

@article{PedersenBjergaard1987RiskOT, title={Risk of therapy-related leukaemia and preleukaemia after Hodgkin's disease. Relation to age, cumulative dose of alkylating agents, and time from chemotherapy.}, author={Jens Pedersen-Bjergaard and Linda A. Specht and Stig Larsen and Jens Ersb\oll and Joachim C. R. Struck and Mark Hansen and H. H. Hansen and Nicholas Nissen}, journal={Lancet}, year={1987}, volume={2 8550}, pages={83-8} }