Risk of subsequent primary malignancies among patients with prior colorectal cancer: a population-based cohort study

  title={Risk of subsequent primary malignancies among patients with prior colorectal cancer: a population-based cohort study},
  author={Jiao Yang and Shuting Li and Meng Lv and Yinying Wu and Zheling Chen and Yanwei Shen and Biyuan Wang and Ling Chen and M. Yi and Jin Yang},
  journal={OncoTargets and therapy},
  pages={1535 - 1548}
Background The site-distribution pattern and relative risk of subsequent primary malignancies (SPMs) in colorectal cancer (CRC) patients remains to be determined. Materials and methods A population-based cohort of 288,390 CRC patients diagnosed between 1973 and 2012 from the Surveillance, Epidemiology, and End Results database was retrospectively reviewed. Standardized incidence ratios were calculated to estimate the relative risk for SPMs. Results The overall risk of SPMs increased in CRC… Expand
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目的 观察合并实体肿瘤病史是否会影响弥漫大B细胞淋巴瘤(DLBCL)患者的治疗效果以及生存情况。 方法Expand


Incidence of Second Primary Malignancies Following Colorectal Cancer: A Distinct Pattern of Occurrence Between Colon and Rectal Cancers and Association of Co-Morbidity with Second Primary Malignancies in a Population-Based Cohort of 98,876 Patients in Taiwan
Patients with CRC were at increased risk for a second cancer, and age, men, COPD, cirrhosis, and dyslipidemia were independent risk factors for SPMs. Expand
Young patients with colorectal cancer have increased risk of second primary cancers.
In young patients with colorectal cancer, the standardized incidence ratio increase was statistically significant and persisted for over 10 years and this significantly increased across all subgroups. Expand
Association between colorectal cancer and urologic cancers.
Previous renal pelvis and ureteral cancers, particularly when diagnosed at an early age, increase the risk for subsequent CRC, and these findings support a possible common pathogenetic mechanism between CRC and urologic cancers and may have implications for screening guidelines. Expand
Proximal Location of Colon Cancer Is a Risk Factor for Development of Metachronous Colorectal Cancer: A Population-Based Study
It is confirmed that proximal colon cancer is a distinct entity, which justifies the reporting of cases of colon cancer according to their location proximal or distal to the splenic flexure, which is in accordance with the increasing incidence and the better prognosis of proximal Colon cancer in various populations. Expand
Clinical Characteristics of Colorectal Cancer Patients With a Second Primary Cancer
Purpose The incidence of colorectal cancer is increasing due to a westernized dietary lifestyle, and improvements in treatment and diagnostic tools have resulted in more patients being confirmed ofExpand
Temporal Trend in Relative Risk of Second Primary Colorectal Cancer
The relative risk of the second primary CRC has increased since early 1990s, and subsequent cancers are being diagnosed at an earlier stage. Expand
Multiple primary malignancies involving primary sporadic colorectal cancer in Japan: incidence of gastric cancer with colorectal cancer patients may be higher than previously recognized
Patients with CRC who were older than 50 years preferentially developed GC synchronously and metachronously should undergo careful perioperative screening for GC. Expand
Double primary malignancy in colorectal cancer patients—MSI is the useful marker for predicting double primary tumors
  • H. Yun, L. Yi, +6 authors W. Lee
  • Medicine
  • International Journal of Colorectal Disease
  • 2008
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Probands of families fulfilling the Amsterdam criteria carry a high risk of rectal cancer and of metachronous CRC, and total proctocolectomy, or total colectomy and a 1-year interval of proctoscopic surveillance should be advised when a highrisk ofrectal cancer can be predicted. Expand
Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
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