Risk of second bone sarcoma following childhood cancer: role of radiation therapy treatment

@inproceedings{Schwartz2014RiskOS,
  title={Risk of second bone sarcoma following childhood cancer: role of radiation therapy treatment},
  author={Boris Schwartz and M A Benadjaoud and {\'E}nora Cl{\'e}ro and Nadia Haddy and Chiraz El-Fayech and Catherine Guibout and C{\'e}cile Teinturier and Odile Oberlin and Cristina Veres and H{\'e}l{\`e}ne D Pacquement and Martine Munzer and T. D. N’guyen and Pierre-Yves Bondiau and Delphine Berchery and A. L. Laprie and Michael W. Hawkins and David Lawrence Winter and Dimitri Lefkopoulos and Jean Chavaudra and Carole Philippart Rubino and I Diallo and Jacques Benichou and Florent de Vathaire},
  booktitle={Radiation and environmental biophysics},
  year={2014}
}
Bone sarcoma as a second malignancy is rare but highly fatal. The present knowledge about radiation-absorbed organ dose-response is insufficient to predict the risks induced by radiation therapy techniques. The objective of the present study was to assess the treatment-induced risk for bone sarcoma following a childhood cancer and particularly the related risk of radiotherapy. Therefore, a retrospective cohort of 4,171 survivors of a solid childhood cancer treated between 1942 and 1986 in… CONTINUE READING
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