Risk of recurrence after a first unprovoked seizure

@article{Berg2008RiskOR,
  title={Risk of recurrence after a first unprovoked seizure},
  author={A. Berg},
  journal={Epilepsia},
  year={2008},
  volume={49}
}
  • A. Berg
  • Published 2008
  • Medicine
  • Epilepsia
The risk of recurrence after a first unprovoked seizure has been examined in numerous observational studies and two large, high‐quality randomized trials. Overall, in untreated individuals, 40–50% can expect a recurrence within 2 years of the initial seizure. Treatment may reduce this risk by as much as half. Those at the greatest risk of recurrence have either an abnormal EEG or an identifiable neurological condition or symptoms consistent with one (“symptomatic”). Status epilepticus and a… Expand
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A cohort of 424 patients was followed to determine the patterns of risk for recurrence after an initial unprovoked seizure, and EEG abnormalities, abnormal neurologic examination findings, and initial partial seizures were identified as significant independent predictors of higher recurrence risks. Expand
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The majority of children with a first unprovoked seizure will not have recurrences, and children with cryptogenic first seizures and a normal EEG whose initial seizure occurs while awake have a particularly favorable prognosis, with a 5-year recurrence risk of only 21%. Expand
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