Risk of peptic ulcer bleeding associated with Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs, low-dose aspirin, and antihypertensive drugs: a case-control study.

@article{Nagata2015RiskOP,
  title={Risk of peptic ulcer bleeding associated with Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs, low-dose aspirin, and antihypertensive drugs: a case-control study.},
  author={Naoyoshi Nagata and Ryota Niikura and Katsunori Sekine and Toshiyuki Sakurai and Takuro Shimbo and Yoshihiro Kishida and Shohei Tanaka and Tomonori Aoki and Hidetaka Okubo and Kazuhiro Watanabe and Chizu Yokoi and Junichi Akiyama and Mikio Yanase and Masashi Mizokami and Naomi Uemura},
  journal={Journal of gastroenterology and hepatology},
  year={2015},
  volume={30 2},
  pages={292-8}
}
BACKGROUND AND AIM The associations between antithrombotic or antihypertensive drugs and peptic ulcer bleeding (PUB) remain unknown, particularly in Asia, where Helicobacter pylori infection is prevalent. This study aims to evaluate the risks of PUB from antithrombotic drugs, angiotensin II receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers, α-blockers, and β-blockers. METHODS This prospective hospital-based case-control study included 230… CONTINUE READING

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