Risk of lymphoproliferative disorders after bone marrow transplantation: a multi-institutional study.

@article{Curtis1999RiskOL,
  title={Risk of lymphoproliferative disorders after bone marrow transplantation: a multi-institutional study.},
  author={Rochelle E. Curtis and Lois B. Travis and Philip A Rowlings and Gerard J Soci{\'e} and Douglas William Kingma and Peter M. Banks and Elaine S. Jaffe and George E. Sale and Mary M. Horowitz and Robert P. Witherspoon and Daniel Shriner and Daniel J. Weisdorf and H. J. Kolb and Keith M. Sullivan and Kathleen A Sobocinski and Robert Peter Gale and Robert Nathaniel Hoover and Joseph F. Jr. Fraumeni and H. Joachim Deeg},
  journal={Blood},
  year={1999},
  volume={94 7},
  pages={2208-16}
}
We evaluated 18,014 patients who underwent allogeneic bone marrow transplantation (BMT) at 235 centers worldwide to examine the incidence of and risk factors for posttransplant lymphoproliferative disorders (PTLD). PTLD developed in 78 recipients, with 64 cases occurring less than 1 year after transplantation. The cumulative incidence of PTLD was 1.0% +/- 0.3% at 10 years. Incidence was highest 1 to 5 months posttransplant (120 cases/10,000 patients/yr) followed by a steep decline to less than… CONTINUE READING

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