Risk of infection and sepsis in severely injured patients related to single nucleotide polymorphisms in the lectin pathway.

@article{Bronkhorst2013RiskOI,
  title={Risk of infection and sepsis in severely injured patients related to single nucleotide polymorphisms in the lectin pathway.},
  author={Maarten W. G. A. Bronkhorst and Miranda A. Z. Lomax and Rolf H. A. M. Vossen and Jan Bakker and Peter Patka and Esther M M Van Lieshout},
  journal={The British journal of surgery},
  year={2013},
  volume={100 13},
  pages={1818-26}
}
BACKGROUND Infectious complications remain a serious threat to patients with multiple trauma. Susceptibility and response to infection is, in part, heritable. The lectin pathway plays a major role in innate immunity. The aim of this study was to assess whether single nucleotide polymorphisms (SNPs) in three key genes within the lectin pathway affect susceptibility to infectious complications in severely injured patients. METHODS A prospective cohort of severely injured patients admitted to a… CONTINUE READING

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