Risk of early-onset proliferative retinopathy in IDDM is closely related to cardiovascular autonomic neuropathy.

@article{Krolewski1992RiskOE,
  title={Risk of early-onset proliferative retinopathy in IDDM is closely related to cardiovascular autonomic neuropathy.},
  author={Andrzej S Krolewski and J I Barzilay and James H. Warram and Blaise C. Martin and Michael A. Pfeifer and Lawrence I. Rand},
  journal={Diabetes},
  year={1992},
  volume={41 4},
  pages={
          430-7
        }
}
Determinants of proliferative diabetic retinopathy (PDR) that occur during the 2nd decade of insulin-dependent diabetes mellitus (IDDM) (early-onset PDR) were investigated in a nested case-control study. From an inception cohort of patients with juvenile-onset IDDM that now has 15-21 yr diabetes duration, the patients with PDR (cases, n = 74) were selected for study along with a random sample of the patients in the cohort without PDR (control subjects, n = 88). The risk of PDR was associated… CONTINUE READING
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