Risk of colorectal neoplasia associated with the adenomatous polyposis coli E1317Q variant.

@article{Hall2009RiskOC,
  title={Risk of colorectal neoplasia associated with the adenomatous polyposis coli E1317Q variant.},
  author={Marni Hall and Evan Liberman and Oleg Dulkart and Lior Galazan and Eyal Sagiv and Einat Shmueli and Dina Kazanov and Aharon Hallak and Menachem Moshkowitz and Ari{\'e} Figer and Sebastian Kraus and Moshe Josef Inbar and Alfred I. Neugut and Nadir Arber},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2009},
  volume={20 9},
  pages={1517-21}
}
BACKGROUND Reports of the risk of colorectal neoplasia associated with a variant of the adenomatous polyposis coli (APC E1317Q) gene are conflicting. Using a case-control design, we investigated this relationship within a clinic-based cohort followed through the Integrated Cancer Prevention Center and the Tel-Aviv Sourasky Medical Center. MATERIALS AND METHODS All study subjects were tested for the APC E1317Q variant at enrollment. Subjects underwent colonoscopic evaluation (+/-biopsy and/or… CONTINUE READING

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