Risk of clinical progression among patients with immunological nonresponse despite virological suppression after combination antiretroviral treatment.

@article{Lapadula2013RiskOC,
  title={Risk of clinical progression among patients with immunological nonresponse despite virological suppression after combination antiretroviral treatment.},
  author={Giuseppe Lapadula and A. Cozzi-lepri and Giulia Marchetti and Andrea Antinori and Alessandro Chiodera and Emanuele Nicastri and Giustino Parruti and Massimo Galli and Andrea Gori and Antonella d'Arminio Monforte},
  journal={AIDS},
  year={2013},
  volume={27 5},
  pages={769-79}
}
BACKGROUND It is unclear whether lack of immunological response despite viral suppression and relatively preserved CD4 T-cell count is associated with increased risk of AIDS or severe non-AIDS events. METHODS Patients initiating first combination antiretroviral therapy (cART) were studied from first viral load 80  copies/ml or less up to AIDS, serious non-AIDS events (malignancies, severe infections, acute kidney injury, cardiovascular events, liver decompensation) or death. Follow-up was… CONTINUE READING
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