Risk of cancer in relatives of prostate cancer probands.

  title={Risk of cancer in relatives of prostate cancer probands.},
  author={Sarah D. Isaacs and Lambertus A Kiemeney and Agnes B. Baffoe-Bonnie and Terri H. Beaty and Patrick Walsh},
  journal={Journal of the National Cancer Institute},
  volume={87 13},
BACKGROUND It is estimated that there will be more than 244,000 new prostate cancer cases diagnosed and that more than 40,000 men will die of this disease during 1995. Evidence exists for a hereditary predisposition to prostate cancer, but the proportion of cases attributable to the inheritance of a specific gene or genes is not large. Some hereditary cancer syndromes involve more than one tumor site, and some studies have reported a familial association between prostate cancer and other… CONTINUE READING
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Mendelian inheritance of familial prostate cancer.

Proceedings of the National Academy of Sciences of the United States of America • 1992