Risk of bias: a simulation study of power to detect study-level moderator effects in meta-analysis

@inproceedings{Hempel2013RiskOB,
  title={Risk of bias: a simulation study of power to detect study-level moderator effects in meta-analysis},
  author={Susanne Hempel and Jeremy N. V. Miles and Marika J. Booth and Zhe Wang and Sally C. Morton and Paul G. Shekelle},
  booktitle={Systematic reviews},
  year={2013}
}
BACKGROUND There are both theoretical and empirical reasons to believe that design and execution factors are associated with bias in controlled trials. Statistically significant moderator effects, such as the effect of trial quality on treatment effect sizes, are rarely detected in individual meta-analyses, and evidence from meta-epidemiological datasets is… CONTINUE READING