Risk of aplastic anemia in patients using antiepileptic drugs.

  title={Risk of aplastic anemia in patients using antiepileptic drugs.},
  author={Kim B Handoko and Patrick C. Souverein and Tjeerd P van Staa and Ronald H. B. Meyboom and Hubert G. M. Leufkens and Toine C. G. Egberts and Patricia M. L. A. van den Bemt},
  volume={47 7},
PURPOSE To assess the association between exposure to antiepileptic drugs (AEDs) and the occurrence of aplastic anemia. METHODS A retrospective case-control study was conducted using data from the U.K. General Practitioners Research Database (GPRD). Cases were defined as patients diagnosed with aplastic anemia. For each case, up to three control patients were matched on age, sex, and medical practice. Cases and controls were compared with respect to AED use. The effects of duration of AED use… CONTINUE READING

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