Risk of Injury Associated with Opioid Use in Older Adults

  title={Risk of Injury Associated with Opioid Use in Older Adults},
  author={David L. Buckeridge and Allen R. Huang and James A. Hanley and Armel Kelome and Kristen Reidel and Aman Verma and Nancy Winslade and Robyn Tamblyn},
  journal={Journal of the American Geriatrics Society},
OBJECTIVES: To estimate the dose‐related risk of injuries in older adults associated with the use of low‐, medium‐, and high‐potency opioids. 
Impact of initiatives to reduce prescription opioid risks on medically attended injuries in people using chronic opioid therapy
The purpose of the study is to determine whether initiatives to improve the safety of opioid prescribing decreased injuries in people using chronic opioid therapy (COT).
Medication and healthcare utilization variation among older adults with pain
While pain is very common in older adults, the associated impact on daily life, including usage of medication and healthcare, varies considerably and often pain remains inadequately treated. It is
Opioid painkiller dependence in a sample of elderly medical inpatients
This study aimed to investigate the prevalence of previous and current prescription opioid dependence among elderly medical inpatients recruited from a large German hospital.
A Standardized, Bundled Approach to Providing Geriatric‐Focused Acute Care
To determine whether a bundled intervention can increase detection of delirium and facilitate safer use of high‐risk medications, a large number of patients with a history of depression and/or substance abuse are enrolled in a single trial.
Recent opioid use and fall-related injury among older patients with trauma
Patients who were admitted for injury in 57 trauma centres in the province of Quebec, Canada, between 2004 and 2014 were included and found that recent opioid use is associated with an increased risk of fall and an increased likelihood of death in older adults.
Reducing fall risk while managing hypotension, pain, and poor sleep in an 83-year-old woman.
Pain, which also affects mood, mobility, and sleep, can be successfully managed to reduce fall risk with the use of effective analgesics.
Opioid Use and the Risk of Falls, Fall Injuries and Fractures among Older Adults: A Systematic Review and Meta-Analysis.
Heterogeneity is present, results suggest an increased risk of falls, fall injuries, and fractures among older adults who used opioids, highlighting the need for opioid education and non-opioid related pain management interventions among older Adults to decrease fall-related risk.
Testosterone deficiency, the unrecognised consequence of the opioid epidemic in men
Testosterone deficiency resulting from chronic opioid use can have a profound effect on health and quality of life, but it often goes unrecognised and untreated. Here the authors review the problem
Incidence and Risk Factors of Long-term Opioid Use in Elderly Trauma Patients
Elderly trauma patients are at risk of long-term opioid use, especially if they had preinjury or early postinjury opioid consumption, according to a retrospective observational multicenter cohort study conducted on registry data.
Newly Initiated Opioid Treatment and the Risk of Fall-Related Injuries
Newly prescribed opioids may trigger injurious falls and the effect lowers over time and is less pronounced with increasing age, but the risk is also higher for fall from height.


A 5‐Year Prospective Assessment of the Risk Associated with Individual Benzodiazepines and Doses in New Elderly Users
To determine the risk of injury associated with the new use of individual benzodiazepines and dosage regimens in the elderly, a large number of patients with a history of depression and substance abuse are surveyed.
Fracture risk associated with the use of morphine and opiates
To study the effect of morphine and opiates on fracture risk, a large number of patients treated with these drugs over a 12-month period had fractures in the past.
Drugs and Falls in Older People: A Systematic Review and Meta‐analysis: II. Cardiac and Analgesic Drugs
The evidence linking specific classes of cardiac and analgesic drugs to falls in older people is evaluated critically to evaluate critically the evidence linking them to falls.
Central Nervous System–Active Medications and Risk for Falls in Older Women
  • K. Ensrud, T. Blackwell, For The Study of Osteoporotic Fractures Research G
  • Medicine, Psychology
    Journal of the American Geriatrics Society
  • 2002
OBJECTIVES: To determine whether current use of central nervous system (CNS)‐active medications, including benzodiazepines, antidepressants, anticonvulsants, and narcotics, increases the risk for
Drugs and Falls in Older People: A Systematic Review and Meta‐analysis: I. Psychotropic Drugs
To evaluate critically the evidence linking psychotropic drugs with falls in older people, a large number of studies have found no link between these drugs and falls in adults over the age of 65.
Increasing deaths from opioid analgesics in the United States
A dramatic increase in poisoning mortality rates is documented and the use of opioid analgesics has increased markedly as part of more aggressive pain management nationwide and this study compared it to sales of opioids nationwide.
Propoxyphene Use by Community‐Dwelling and Institutionalized Elderly Medicare Beneficiaries
This work aims to provide the first comparable national prevalence estimates on use of propoxyphene by elderly Medicare beneficiaries living in the community and institutions and to determine whether institutionalized beneficiaries are at a greater risk for receiving propoxymhene than community‐dwelling beneficiaries.
Opioid analgesics and the risk of hip fracture in the elderly: codeine and propoxyphene.
We studied the risk of hip fracture in elderly persons receiving prescriptions for two commonly prescribed opioid analgesics--codeine and propoxyphene. Using automated prescription and
The Risk of Motor Vehicle Accidents Involving Drivers With Prescriptions for Codeine or Tramadol
A prospective cohort design with data from national population–based registries and observation of >8 million person‐years was used in order to examine whether a driver who has filled a prescription for codeine or tramadol is at increased risk of being involved in a road accident resulting in injury to persons.
Central nervous system active medications and risk for fractures in older women.
Community-dwelling older women taking narcotics have an increased risk for any nonspine fracture, and those taking antidepressants have a greater risk for nonspine fractures, including hip fracture.