Risk of Acute Pancreatitis in Type 2 Diabetes and Risk Reduction on Anti-Diabetic Drugs: A Population-Based Cohort Study in Taiwan

@article{Lai2011RiskOA,
  title={Risk of Acute Pancreatitis in Type 2 Diabetes and Risk Reduction on Anti-Diabetic Drugs: A Population-Based Cohort Study in Taiwan},
  author={Shih‐Wei Lai and Chih-Hsin Muo and Kuan Fu Liao and Fung-Chang Sung and Pei-Chun Chen},
  journal={The American Journal of Gastroenterology},
  year={2011},
  volume={106},
  pages={1697-1704}
}
OBJECTIVES:The objective of this study was to assess the risk of acute pancreatitis among patients with type 2 diabetes mellitus (DM) and identify the roles of co-morbidities and anti-diabetic drugs.METHODS:From claims data of one million enrollees randomly sampled from a population covered by the Taiwan National Health Insurance, 19,518 adults with type 2 DM diagnosed between 2000 and 2005 were identified. In addition, 78,072 DM-free persons, frequency matched with sex, age, and index year for… 
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Highly Influential Citations
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149 Citations

Increased Risk of Acute Pancreatitis in Patients with Type 2 Diabetes: An Observational Study Using a Japanese Hospital Database

The risk estimates in Japanese patients with diabetes were in agreement with the ones reported in previous studies, and the elevated risk of acute pancreatitis in patients with Diabetes mellitus would be generalized in different locations/populations.

National trends in incidence and outcomes of acute pancreatitis among type 2 diabetics and non-diabetics in Spain (2001-2011).

Incretin-based pharmacotherapy and risk of adverse pancreatic events in the ethnic Chinese with diabetes mellitus: A population-based study in Taiwan.

Acute Pancreatitis in Patients with Type 2 Diabetes Mellitus Treated with Dipeptidyl Peptidase-4 Inhibitors: A Population-Based Nested Case-Control Study

It was found that underlying diseases and severity of diabetes but not DPP-4 inhibitor use were associated with acute pancreatitis, and the adjusted risk of acute pancitis was found to be increased significantly in patients with gallstone disease.

Effect of Diabetes on Severity and Hospital Mortality in Patients With Acute Pancreatitis

Although diabetes may adversely affect the disease process of AP, it seems to protect patients from AP-related mortality, and AP patients with diabetes were associated with a lower risk of hospital mortality.

Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: A population-based case-control study in Taiwan.

Type 2 diabetes mellitus and the risk of acute pancreatitis: a meta-analysis

The relationship between type 2 diabetes mellitus and an increased risk of acute pancreatitis strongly support the biological mechanisms of the association.

Severity and natural history of acute pancreatitis in diabetic patients.

Incretin-Based Therapy and Risk of Acute Pancreatitis: A Nationwide Population-Based Case-Control Study

It is suggested that the use of incretin-based drugs appears not to be associated with an increased risk of acute pancreatitis, and findings were similar in current versus ever drug users and in patients with pancreatitis risk factors.

Digoxin use may increase the relative risk of acute pancreatitis: A population-based case-control study in Taiwan.

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