Risk models predicting survival after reduced-intensity transplantation for myelofibrosis.

@article{Alchalby2012RiskMP,
  title={Risk models predicting survival after reduced-intensity transplantation for myelofibrosis.},
  author={Haefaa Alchalby and Dinah-Rohina Yunus and Tatjana Zabelina and Guido Kobbe and Ernst Holler and Martin Bornhaeuser and Rainer Schwerdtfeger and Wolfgang Andreas Bethge and Hans Michael Kvasnicka and Guntram B{\"u}sche and Francis Ayketang Ayuk and Ulrike Bacher and Axel Rolf Zander and Nicolaus Kr{\"o}ger},
  journal={British journal of haematology},
  year={2012},
  volume={157 1},
  pages={
          75-85
        }
}
To define a prognostic model for predicting outcome of reduced-intensity allogeneic stem cell transplantation (RIC-ASCT) for myelofibrosis we evaluated 150 homogeneously treated patients and developed a new risk score for overall survival (OS). In a multivariate Cox model for OS, only JAK2 V617F wild-type, age ≥57 years and constitutional symptoms were independently predictive for OS (Hazard Ratio: 2·02; 2·43 and 2·80 respectively). Depending on the presence of one, two or all of these factors… CONTINUE READING
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