Risk for second nonlymphoid neoplasms in chronic lymphocytic leukemia.

  title={Risk for second nonlymphoid neoplasms in chronic lymphocytic leukemia.},
  author={Constantin A. Dasanu and D. Alexandrescu},
  journal={MedGenMed : Medscape general medicine},
  volume={9 4},
Major advances have occurred in understanding the biology, immunology, and modalities of treatment of chronic lymphocytic leukemia (CLL) in the last decade. B-cell CLL is the most common type of leukemia occurring in the US and Western nations. B-cell CLL is characterized by progressive defects in both cell-mediated and humoral-mediated immunity. B-lymphocyte defects, low gammaglobulin levels, and quantitative and functional T-cell defects have been documented in the setting of CLL. In concert… CONTINUE READING


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