Risk for retinitis in patients with AIDS can be assessed by quantitation of threshold levels of cytomegalovirus DNA burden in blood.

@article{Rasmussen1997RiskFR,
  title={Risk for retinitis in patients with AIDS can be assessed by quantitation of threshold levels of cytomegalovirus DNA burden in blood.},
  author={Lucy Rasmussen and Donato Zipeto and Richard A Wolitz and Anthony Dowling and Brad Efron and Thomas C. Merigan},
  journal={The Journal of infectious diseases},
  year={1997},
  volume={176 5},
  pages={1146-55}
}
Cytomegalovirus (CMV) retinitis in patients infected with human immunodeficiency virus (HIV) is a significant clinical problem. Seventy-five patients with CD4 T cell counts <100/mm3 were monitored prospectively every 2 months for CMV DNA burden. The target for DNA amplification was a 162-bp fragment from the CMV immediate early gene. CMV DNA burden, at levels of > or =320 in white blood cells or > or =32 in plasma (P = .001), particularly when sustained (P = .005 and .008, respectively… CONTINUE READING