Risk factors relating blood markers of inflammation and nutritional status to survival in cachectic geriatric patients in a randomized clinical trial.

@article{Yeh2004RiskFR,
  title={Risk factors relating blood markers of inflammation and nutritional status to survival in cachectic geriatric patients in a randomized clinical trial.},
  author={Shing-shing Yeh and Alice Hafner and Chin-Kuo Chang and Daniel M. Levine and Thomas S. Parker and Michael W. Schuster},
  journal={Journal of the American Geriatrics Society},
  year={2004},
  volume={52 10},
  pages={1708-12}
}
OBJECTIVES To evaluate the effect of proinflammatory cytokines, their receptors, and nutritional indicators (at baseline and after 12 weeks of megestrol acetate (MA) treatment) upon long-term survival in geriatric cachectic patients without active acute infections, inflammation, or cancer. DESIGN Randomized clinical trial with placebo or MA treatment for 12 weeks and then follow-up for more than 4 years. SETTING Veterans Affairs nursing home in Northport, New York. PARTICIPANTS Nursing… CONTINUE READING
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