Risk factors of Ganciclovir-related neutropenia after allogeneic stem cell transplantation: a retrospective monocentre study on 547 patients.

@article{Venton2014RiskFO,
  title={Risk factors of Ganciclovir-related neutropenia after allogeneic stem cell transplantation: a retrospective monocentre study on 547 patients.},
  author={Geoffroy Venton and Roberto Crocchiolo and Sabine F{\"u}rst and Angela M Granata and C Oudin and Catherine Faucher and Diane Coso and R{\'e}da Bouabdallah and Pierre Berger and Norbert Vey and Patrick Ladaique and Christian Chabannon and M le Merlin and Didier Blaise and J El-cheikh},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2014},
  volume={20 2},
  pages={160-6}
}
Cytomegalovirus (CMV) infection is a serious complication that may occur in the weeks or months following bone marrow transplantation. However, both Ganciclovir and the CMV infection itself can cause marrow toxicity, notably neutropenia, that may consequently expose these immunosuppressed patients to life-threatening bacterial and/or fungal infections. The aim of this retrospective study was to identify factors associated with the occurrence of grade III-IV neutropenia among patients receiving… CONTINUE READING