Risk factors for pancreatic cancer: underlying mechanisms and potential targets

@inproceedings{Kolodecik2013RiskFF,
  title={Risk factors for pancreatic cancer: underlying mechanisms and potential targets},
  author={Thomas R. Kolodecik and Christine A. Shugrue and Munish Ashat and E C Thrower},
  booktitle={Front. Physiol.},
  year={2013}
}
PURPOSE OF THE REVIEW Pancreatic cancer is extremely aggressive, forming highly chemo-resistant tumors, and has one of the worst prognoses. The evolution of this cancer is multi-factorial. Repeated acute pancreatic injury and inflammation are important contributing factors in the development of pancreatic cancer. This article attempts to understand the common pathways linking pancreatitis to pancreatic cancer. RECENT FINDINGS Intracellular activation of both pancreatic enzymes and the… CONTINUE READING
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