Risk factors for invasive squamous cell carcinoma of the vulva and vagina—Population‐based case–control study in Denmark

@article{Madsen2008RiskFF,
  title={Risk factors for invasive squamous cell carcinoma of the vulva and vagina—Population‐based case–control study in Denmark},
  author={Birgitte Schütt Madsen and Helle L. Jensen and Adriaan J. C. van den Brule and Jan Wohlfahrt and Morten Frisch},
  journal={International Journal of Cancer},
  year={2008},
  volume={122}
}
The etiology of vulvar and vaginal squamous cell carcinoma (VV‐SCC) has received little attention. A total of 182 women with invasive VV‐SCC (116 with VV‐SCCvulva, 66 with VV‐SCCvagina), 164 uterine corpus cancer controls and 518 population controls were interviewed in a population‐based case–control study in Denmark, and 87 (48%) of the VV‐SCC cases had tissue samples examined for human papillomavirus (HPV) DNA using the GP5+/6+ PCR‐EIA assay and subsequent reverse line blotting for HPV typing… 

Risk Factors for Squamous Cell Carcinoma of the Penis—Population-Based Case-Control Study in Denmark

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Prevalence and type distribution of human papillomavirus in squamous cell carcinoma and intraepithelial neoplasia of the vulva

HPV vaccination targeting these HPV types may prevent a substantial number of vulvar lesions, and the predominant high‐risk HPV type was HPV16, followed by HPV33 and HPV18.

Histological characteristics of human papilloma‐virus‐positive and ‐negative invasive and in situ squamous cell tumours of the penis

About half of invasive penile squamous carcinomas in this study were hrHPV‐positive, most notably to HPV 16, and probably arose through in situ lesions whereas the other half ofvasive penile lesions appeared to be unrelated tohrHPV.

Human papillomavirus and p16 in squamous cell carcinoma and intraepithelial neoplasia of the vagina

It is suggested that vaccination against HPV might prevent a substantial proportion of vaginal neoplasia and highlight the need for further studies of the possible clinical value of p16 testing in these patients.

Large contribution of human papillomavirus in vaginal neoplastic lesions: a worldwide study in 597 samples.

Searching beyond the usual papillomavirus suspects in squamous carcinomas of the vulva, penis and head and neck.

Presence of human papillomavirus (HPV) in vulvar squamous cell carcinoma (VSCC) and sentinel node.

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