Risk factors for invasive aspergillosis in acute myeloid leukemia patients prophylactically treated with posaconazole.

@article{Michallet2011RiskFF,
  title={Risk factors for invasive aspergillosis in acute myeloid leukemia patients prophylactically treated with posaconazole.},
  author={Mauricette Michallet and Mohamad A Sobh and St{\'e}phane Morisset and Samira Kraghel and Franck Emmanuel Nicolini and X. Thomas and Anne-Lise Bienvenu and St{\'e}phane Picot and M C Nicolle and Philippe Vanhems},
  journal={Medical mycology},
  year={2011},
  volume={49 7},
  pages={681-7}
}
Invasive aspergillosis (IA) is an important cause of morbidity and mortality in neutropenic patients with hematological malignancies. To investigate the immediate and mid-term benefits of posaconazole prophylaxis in AML patients undergoing first induction chemotherapy and to study the infection risk factors, we prospectively studied the IA incidence in these patients at our hospital between years 2007 and 2008; then we compared them to a matched control group without prophylaxis. There were 55… CONTINUE READING