Risk factors for hepatocellular carcinoma in a Japanese population: a nested case-control study.

BACKGROUND Epidemiologic studies have shown effects of lifestyle-related factors on risk for hepatocellular carcinoma. However, few cohort studies have incorporated, in a strict and in-depth manner, hepatitis B virus (HBV) and hepatitis C virus (HCV) infections or investigated synergism between such factors. METHODS We conducted a nested case-control… (More)