Risk factors for hepatic encephalopathy in patients with cirrhosis and refractory ascites: relevance of serum sodium concentration.

@article{Guevara2010RiskFF,
  title={Risk factors for hepatic encephalopathy in patients with cirrhosis and refractory ascites: relevance of serum sodium concentration.},
  author={M{\'o}nica Ladr{\'o}n de Guevara and Mar{\'i}a Eugenia Baccaro and Jos{\'e} R{\'i}os and Marta Mart{\'i}n-Llah{\'i} and Juan Uriz and Luis Ruiz del Arbol and Ram{\'o}n Planas and Alberto Monescillo and Carlos Guarner and Javier Crespo and Rafael Ba{\~n}ares and Vicente Arroyo and Pere Gin{\`e}s},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2010},
  volume={30 8},
  pages={1137-42}
}
Hyponatraemia is common in patients with advanced cirrhosis and is associated with remarkable changes in brain cells, particularly a reduction in myoinositol and other intracellular organic osmolytes related to the hypo-osmolality of the extracellular fluid. It has been recently suggested that hyponatraemia may be an important factor associated with the… CONTINUE READING