Risk factors for chronic rejection in renal allograft recipients.

  title={Risk factors for chronic rejection in renal allograft recipients.},
  author={P. Stephen Almond and Arthur J. Matas and Kristen J. Gillingham and David L. Dunn and William D. Payne and Paul F. Gores and Ranier Gruessner and J. Najarian},
  volume={55 4},
          752-6; discussion 756-7
Chronic rejection is a major barrier to long-term renal allograft survival. Cyclosporine, though effective at reducing graft loss to acute rejection, has had little impact on the incidence of chronic rejection. Between June 2, 1986 and January 22, 1991, 587 kidney-alone transplants (566 patients) were performed, and had been entered into our renal transplant database and had at least 1 year of follow-up: 103 with biopsy-proven chronic rejection (37 living-related donor, 66 cadaver) and 484… CONTINUE READING
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