Risk factors for autoimmune-mediated congenital heart block

@inproceedings{Meisgen2017RiskFF,
  title={Risk factors for autoimmune-mediated congenital heart block},
  author={Sabrina Meisgen},
  year={2017}
}
Placental transfer of maternal Ro/SSA and La/SSB autoantibodies during pregnancy is associated with conduction disturbances and inflammation in the developing fetal heart, termed autoimmune-mediated congenital heart block (CHB). Maternal Ro/SSA and La/SSB autoantibodies are the main risk factors associated with the fetal cardiac manifestations to date, however, the low recurrence rate despite persisting autoantibodies in subsequent pregnancies indicates that additional factors determine fetal… CONTINUE READING

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