Risk factors for acute kidney injury in critically ill patients receiving high intravenous doses of colistin methanesulfonate and/or other nephrotoxic antibiotics: a retrospective cohort study

@inproceedings{Rocco2013RiskFF,
  title={Risk factors for acute kidney injury in critically ill patients receiving high intravenous doses of colistin methanesulfonate and/or other nephrotoxic antibiotics: a retrospective cohort study},
  author={Monica Rocco and Luca M. Montini and Elisa Alessandri and Mario Venditti and Amalia Laderchi and Pascale De Gennaro and Giammarco Raponi and Michela Vitale and Paolo Pietropaoli and Massimo Antonelli},
  booktitle={Critical care},
  year={2013}
}
INTRODUCTION Use of colistin methanesulfonate (CMS) was abandoned in the 1970s because of excessive nephrotoxicity, but it has been reintroduced as a last-resort treatment for extensively drug-resistant infections caused by gram-negative bacteria (Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumonia). We conducted a retrospective cohort study to evaluate risk factors for new-onset acute kidney injury (AKI) in critically ill patients receiving high intravenous doses of colistin… CONTINUE READING
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