Risk factors for Clostridium difficile toxin-associated diarrhea.

  title={Risk factors for Clostridium difficile toxin-associated diarrhea.},
  author={Edgar Brown and George Harrison Talbot and Peter Axelrod and Matthew T. Provencher and C Hoegg},
  journal={Infection control and hospital epidemiology},
  volume={11 6},
The hospital-wide attack rate for Clostridium difficile-associated diarrhea at our tertiary-care university hospital was 0.02 per 100 patient discharges (0.02%) in 1982, but 0.41% and 1.47% in 1986 and 1987, respectively, with a peak incidence of 2.25% in the fourth quarter of 1987. Hospital antibiotic usage patterns showed concurrent increased use of third-generation cephalosporins, and intravenous vancomycin and metronidazole. Thirty-seven cases selected for study were older than 37 control… CONTINUE READING
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