Risk factors associated with secondary sarcomas in childhood cancer survivors: a report from the childhood cancer survivor study.

@article{Henderson2012RiskFA,
  title={Risk factors associated with secondary sarcomas in childhood cancer survivors: a report from the childhood cancer survivor study.},
  author={Tara O Henderson and Preetha Rajaraman and M. Joshua Stovall and Louis Sandy Constine and Aliza Olive and Susan A. Smith and Ann Mertens and Anna T. Meadows and Joseph Phillip Neglia and Sue Hammond and Jeremy Whitton and R. Eugene Curtis and Leslie L. Robison and Lisa Diller},
  journal={International journal of radiation oncology, biology, physics},
  year={2012},
  volume={84 1},
  pages={
          224-30
        }
}
PURPOSE Childhood cancer survivors have an increased risk of secondary sarcomas. To better identify those at risk, the relationship between therapeutic dose of chemotherapy and radiation and secondary sarcoma should be quantified. METHODS AND MATERIALS We conducted a nested case-control study of secondary sarcomas (105 cases, 422 matched controls) in a cohort of 14,372 childhood cancer survivors. Radiation dose at the second malignant neoplasm (SMN) site and use of chemotherapy were estimated… CONTINUE READING
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Risk, Risk Factors, and Surveillance of Subsequent Malignant Neoplasms in Survivors of Childhood Cancer: A Review.

  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2018
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