Risk factors and survival by HPV-16 E6 and E7 antibody status in human papillomavirus positive head and neck cancer.

@article{Smith2010RiskFA,
  title={Risk factors and survival by HPV-16 E6 and E7 antibody status in human papillomavirus positive head and neck cancer.},
  author={Elaine M. Smith and Michael Pawlita and Linda M. Rubenstein and Thomas H. Haugen and Eva Ham{\vs}{\'i}kov{\'a} and Lubomir P. Turek},
  journal={International journal of cancer},
  year={2010},
  volume={127 1},
  pages={111-7}
}
High-risk human papillomavirus types (HPV-HR) are associated with head and neck cancer (HNC) risk and better survival. Most patients with HPV-HR DNA-positive tumors develop anti-HPV E6/E7 antibodies; however, it is unclear whether those who mount an immune response have similar risk factors or clinical outcomes as those who do not. HPV-16 DNA tumor-positive HNC cases were evaluated for HPV-16 E6 and E7 antibodies using a GST capture ELISA system. Among 57 HPV-16 DNA tumor-positive HNC cases, 67… CONTINUE READING

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