Risk factors and outcomes associated with severe clostridium difficile infection in children.

@article{Kim2012RiskFA,
  title={Risk factors and outcomes associated with severe clostridium difficile infection in children.},
  author={Jason Y Kim and Julia F Shaklee and Sarah Smathers and Priya Prasad and Lindsey Asti and Joan Zoltanski and Michael J Dul and Michelle M. Nerandzic and Susan E. Coffin and Philip Toltzis and Theoklis Z Zaoutis},
  journal={The Pediatric infectious disease journal},
  year={2012},
  volume={31 2},
  pages={134-8}
}
BACKGROUND The incidence and severity of Clostridium difficile infection (CDI) is increasing among adults; however, little is known about the epidemiology of CDI among children. METHODS We conducted a nested case-control study to identify the risk factors for and a prospective cohort study to determine the outcomes associated with severe CDI at 2 children's hospitals. Severe CDI was defined as CDI and at least 1 complication or ≥2 laboratory or clinical indicators consistent with severe… CONTINUE READING