Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome.

@article{Boelens2009RiskFA,
  title={Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome.},
  author={Jaap Jan Boelens and Vanderson Rocha and Mieke Aldenhoven and Robert Wynn and Anne O'meara and G{\'e}rard Michel and Irina Ionescu and Suhag H Parikh and V. Prasad and Paul M Szabolcs and Maria L. Escolar and Eliane Gluckman and Marina Cavazzana-Calvo and Joanne Kurtzberg},
  journal={Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation},
  year={2009},
  volume={15 5},
  pages={618-25}
}
Allogeneic stem cell transplantation (SCT) is considered effective in preventing disease progression in patients with Hurler syndrome (HS). Unrelated umbilical cord blood (UCB) grafts are suggested as an alternative to bone marrow (BM) or peripheral blood stem cells (PBSC). We studied 93 HS patients receiving an UCB graft to analyze risk factors for outcomes. The median time from diagnosis to transplant was 4.6 months, median follow-up was 29 months, and median number of nucleated CB cells… CONTINUE READING
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