Risk evaluation, prophylaxis, and treatment of tumor lysis syndrome: consensus of an Italian expert panel.

@article{Pession2011RiskEP,
  title={Risk evaluation, prophylaxis, and treatment of tumor lysis syndrome: consensus of an Italian expert panel.},
  author={Andrea Pession and Riccardo Masetti and Gianluca Gaidano and Patrizia Tosi and Giovanni Rosti and Massimo Aglietta and Giorgina Specchia and Fulvio Porta and Fabrizio Pane},
  journal={Advances in therapy},
  year={2011},
  volume={28 8},
  pages={684-97}
}
INTRODUCTION Tumor lysis syndrome (TLS) is a life-threatening complication in patients with hematological disease and/or solid tumors that results from rapid, large-scale tumor necrosis occurring spontaneously, or more commonly, as a result of chemotherapy. TLS is characterized by metabolic and electrolyte imbalances that include hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia. Identification of risk groups as well as early detection of TLS is crucial for the establishment of… CONTINUE READING
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