Risk and clinical significance of developing antibodies induced by topical thrombin preparations.

Abstract

OBJECTIVE TO determine the clinical relevance, prevalence, and risk of antibody development in patients exposed to topical bovine thrombin preparations. DESIGN A prevalence study of individuals previously exposed to topical bovine thrombin was done by screening using Western blot assay to detect antibodies against bovine thrombin preparations. SETTING A… (More)

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