Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study.

@article{Klein2013RiskAI,
  title={Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study.},
  author={Ronald Klein and Chelsea Myers and Stacy M. Meuer and Ronald E. Gangnon and Theru A. Sivakumaran and Sudha K. Iyengar and Kristine E. Lee and Barbara E. K. Klein},
  journal={JAMA ophthalmology},
  year={2013},
  volume={131 3},
  pages={383-92}
}
OBJECTIVE To describe the relationships of risk alleles in complement factor H (CFH, rs1061170) and age-related maculopathy susceptibility 2 (ARMS2, rs10490924) to the incidence and progression of age-related macular degeneration (AMD) during a 20-year period. METHODS There were 4282 persons aged 43 to 86 years at the baseline examination in 1988-1990… CONTINUE READING