Risk Factors of Vasopressor-Induced Symmetrical Peripheral Gangrene

  title={Risk Factors of Vasopressor-Induced Symmetrical Peripheral Gangrene},
  author={Jung Woo Kwon and Min Ki Hong and Bo Young Park},
  journal={Annals of Plastic Surgery},
  pages={622 - 627}
Background Symmetrical peripheral gangrene (SPG) is an uncommon syndrome showing symmetrical gangrene in acral regions without evidence of large-vessel occlusion or vasculitis. Intravenous vasopressors are frequently used to manage hemodynamically unstable patients. There have been few reports about SPG after using inotropics. However, risk factors for SPG have not been extensively studied. Therefore, the objective of this study was to analyze several cases of SPG and identify risk factors for… 
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PRACTIC E Sepsis in Critical Care
)) AND (("2011"[Date Publication] : "2021"[Date Publication])) with filters Clinical study and Age 80+
One Sepsis Fits All ? Are There Different Phenotypes of Sepsis ? Diagnostic Approaches and Therapies
)) AND (("2011"[Date Publication] : "2021"[Date Publication])) with filters Clinical study and Age 80+


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Postpartum Peripheral Symmetrical Gangrene: A Case Report
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Symmetrical peripheral gangrene and disseminated intravascular coagulation.
Review of the medical literature shows a high association between SPG and DIC, and Symmetrical peripheral gangrene should be considered a cutaneous marker of DIC.
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Lack of any prospective study on the profile and outcome of patients with SPG prompted this work to undertake the present work.
Symmetrical peripheral gangrene and the use of systemic hyperbaric oxygen therapy.
This case report supports the view that early amputation should be avoided allowing for stabilisation of the gangrene so that no viable tissue is sacrificed and further research is necessary to establish the pathogenesis and suitable treatment pathways.
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In all four patients with bilateral pedal ischaemia the syndrome developed in association with noradrenaline administration, sepsis and DIC, despite a high cardiac output and a low calculated systemic vascular resistance index.
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2 cases of severe skin necrosis after high dose vasopressor infusion to maintain the recommended MAP in septic shock are reported, which required amputations in both cases.
Symmetrical peripheral gangrene: a rare but dreadful complication of sepsis.
  • M. Parmar
  • Medicine
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
  • 2002
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