Risk Factors for Overall Survival Outcome in Surgically Treated Human Papillomavirus-Negative and Positive Patients with Oropharyngeal Cancer.

@article{Wuerdemann2017RiskFF,
  title={Risk Factors for Overall Survival Outcome in Surgically Treated Human Papillomavirus-Negative and Positive Patients with Oropharyngeal Cancer.},
  author={Nora Wuerdemann and Claus Wittekindt and Shachi Jenny Sharma and Elena-Sophie Prigge and Miriam Reuschenbach and Stefan Gattenloehner and Jens Klu\ssmann and Steffen Wagner},
  journal={Oncology research and treatment},
  year={2017},
  volume={40 6},
  pages={320-327}
}
INTRODUCTION This study reports the oncological outcome of a non-selected series of patients with human papillomavirus(HPV)-positive and -negative oropharyngeal squamous cell carcinoma (OSCC) preferentially managed with upfront surgery. METHODS Consecutive OSCC cases (n = 378) diagnosed from 2000 to 2010 in our department were evaluated for risk factors, HPV association, therapy and overall survival (OS). HPV status was determined by combined DNA and p16 testing, and treatment was defined as… CONTINUE READING

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