Risk Factors for Ovarian Cancer: An Overview with Emphasis on Hormonal Factors

  title={Risk Factors for Ovarian Cancer: An Overview with Emphasis on Hormonal Factors},
  author={F. Salehi and Lesley Dunfield and K. Phillips and D. Krewski and B. Vanderhyden},
  journal={Journal of Toxicology and Environmental Health, Part B},
  pages={301 - 321}
  • F. Salehi, Lesley Dunfield, +2 authors B. Vanderhyden
  • Published 2008
  • Medicine
  • Journal of Toxicology and Environmental Health, Part B
  • Ovarian cancer is the fifth most frequently occurring cancer among women and leading cause of gynecological cancer deaths in North America. Although the etiology of ovarian cancer is not clear, certain factors are implicated in the etiology of this disease, such as ovulation, gonadotropic and steroid hormones, germ cell depletion, oncogenes and tumor suppressor genes, growth factors, cytokines, and environmental agents. Family history of breast or ovarian cancer is a prominent risk factor for… CONTINUE READING
    144 Citations
    Analysis of ovarian cancer and associated risk factors
    • B. Patel, D. Mital
    • Medicine, Computer Science
    • Int. J. Medical Eng. Informatics
    • 2015
    Recent progress in the diagnosis and treatment of ovarian cancer
    • 517
    Attributable causes of breast cancer and ovarian cancer in China: Reproductive factors, oral contraceptives and hormone replacement therapy
    • 27
    • Highly Influenced
    BRCA and Early Events in the Development of Serous Ovarian Cancer
    • 49
    • PDF
    Development of a Mouse Model of Menopausal Ovarian Cancer
    • 12
    • PDF
    Ovarian cancer: risk factors, treatment and management.
    • 56


    Possible role of ovarian epithelial inflammation in ovarian cancer.
    • 543
    • PDF
    Hormonal etiology of epithelial ovarian cancer, with a hypothesis concerning the role of androgens and progesterone.
    • H. Risch
    • Biology, Medicine
    • Journal of the National Cancer Institute
    • 1998
    • 758
    • PDF
    Factors related to inflammation of the ovarian epithelium and risk of ovarian cancer.
    • 336
    Endocrine factors in common epithelial ovarian cancer.
    • 215
    • 48
    Hormonal factors and the risk of invasive ovarian cancer: a population-based case-control study.
    • 138
    • Highly Influential
    Endocrine signaling in ovarian surface epithelium and cancer.
    • 77
    • Highly Influential
    • PDF
    Family history of ovarian cancer
    • 14
    Epithelial Ovarian Cancer Risk Among Women With Polycystic Ovary Syndrome
    • 304