Risk Factors for Gallbladder Cancer and Cholangiocarcinoma: Similarities, Differences and Updates

@article{Rustagi2011RiskFF,
  title={Risk Factors for Gallbladder Cancer and Cholangiocarcinoma: Similarities, Differences and Updates},
  author={T. Rustagi and C. Dasanu},
  journal={Journal of Gastrointestinal Cancer},
  year={2011},
  volume={43},
  pages={137-147}
}
IntroductionFar-ranging variation in the incidence of gallbladder cancer (GBC) and cholangiocarcinoma (CCA) in different geographic regions on the globe may reflect the risk factor distribution for these tumorsMethodsThe authors give a comprehensive review on the known risk factors for GBC and CCA, and analyze both similarities and differences between the risk factors for the two main types of biliary cancerDiscussion and ConclusionLeading risk factors for GBC include gallstones, female gender… Expand
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References

SHOWING 1-10 OF 180 REFERENCES
Risk factors for cholangiocarcinoma
  • T. Ben-Menachem
  • Medicine
  • European journal of gastroenterology & hepatology
  • 2007
TLDR
The study by Ahrens et al. finds that obesity and gallstones are risk factors for developing extrahepatic cholangiocarcinoma in men patients and the association of obesity with the risk of developing cholangsiocARCinoma persisted for all anatomic subsites. Expand
Primary gallbladder cancer: recognition of risk factors and the role of prophylactic cholecystectomy.
The objective of this article is to review the available literature on the epidemiology, predisposing factors, and conditions associated with primary gallbladder cancer, and to discuss the role ofExpand
Risk factors for biliary tract carcinogenesis.
  • R. Chapman
  • Medicine
  • Annals of oncology : official journal of the European Society for Medical Oncology
  • 1999
TLDR
Cholangiocarcinoma has a worldwide distribution which accounts for about 10-15% of all cases of primary hepatobiliary malignancy and has been weakly linked to hepatitis C infection. Expand
Risk factors for intrahepatic and extrahepatic cholangiocarcinoma in the United States: a population-based case-control study.
  • T. Welzel, B. Graubard, +4 authors K. McGlynn
  • Medicine
  • Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2007
TLDR
Several novel associations with ECC and ICC were identified, including HCV infection, chronic nonalcoholic liver disease, and obesity, all of which are increasing in incidence, and smoking, which were associated only with ICC. Expand
A Case-Control Assessment of Risk Factors for Gallbladder Carcinoma
TLDR
Gallbladder cancer subjects were predominantly female, more likely to report previous gallstonesymptomology, and to smoke, and while gallstones were notuniversally isolated from carcinoma patients at cholecystectomy, when present, they were less frequentlyclassified as cholesterol gallstones based on visual inspection. Expand
Gallbladder cancer worldwide: Geographical distribution and risk factors
TLDR
Differences in incidence ratios point to variations in gallbladder cancer aetiology in different populations, but interventions able to prevent obesity, cholecystitis and gallstone formation should be assessed. Expand
High lifetime risk of cancer in primary sclerosing cholangitis.
TLDR
Patients with PSC and IBD have a high long-term risk of developing CRC and this risk is about threefold higher than the risk for CCA, and both malignancies are associated with decreased survival. Expand
Incidence and Risk Factors for Cholangiocarcinoma in Primary Sclerosing Cholangitis
TLDR
Almost 7% of PSC patients later developed CCA over a mean follow-up of 11.5 yr, which is dramatically higher than the rates in the general population, and variceal bleeding is a major risk factor for the later development of CCA. Expand
Risk Factors for Intrahepatic and Extrahepatic Cholangiocarcinoma: A Hospital-Based Case–Control Study
TLDR
Liver cirrhosis and chronic HCV infection are possible risk factors for ICC but not ECC, and heavy alcohol consumption is a risk factor for both ICC and ECC. Expand
Risk factors and clinical presentation of hepatobiliary carcinoma in patients with primary sclerosing cholangitis: A case‐control study
TLDR
Clinical and biochemical presentation of PSC patients with and without hepatobiliary carcinoma did not differ during the year before cancer diagnosis/Ltx, and smoking seems to be a risk factor for developing hepatobility carcinoma in patients with PSC. Expand
...
1
2
3
4
5
...